Malaria

Animal Models

  • Various mouse strains
  • Rhesus macaque and squirrel monkeys

Study Types

  • Vaccine testing
  • Therapeutics testing
  • PK/safety testing

In vitro Services

  • Sample processing
  • Giemsa stained blood smears

Representative Publications

 

Anti-PfGARP Activates Programmed Cell Death of Parasites and Reduces Severe Malaria

E. Epstein, K. Tewari, K. E. Lyke, B. K. L. Sim, P. F. Billingsley, M. B. Laurens, A. Gunasekera, S. Chakravarty, E. R. James, M. Sedegah, A. Richman, S. Velmurugan, S. Reyes, M. Li, K. Tucker, A. Ahumada, A. J. Ruben, T. Li, R. Stafford, A. G. Eappen, C. Tamminga, J. W. Bennett, C. F. Ockenhouse, J. R. Murphy, J. Komisar, N. Thomas, M. Loyevsky, A. Birkett, C. V. Plowe, C. Loucq, R. Edelman, T. L. Richie, R. A. Seder, S. L. Hoffman. Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8+ T Cell Immunity. Science 28 Oct 2011: Vol. 334, Issue 6055, pp. 475-480. DOI: 10.1126/science.1211548.

Yin J, Vahey MT, Dai A, Lewis MG, Arango T, Yalley-Ogunro J, Greenhouse J, Mendoza K, Khan A, Sardesai NY, Weiss W, Komisar J, Boyer JD. Plasmodium inui infection reduces the efficacy of a simian immunodeficiency virus DNA vaccine in a rhesus macaque model through alteration of the vaccine-induced immune response. J Infect Dis. 2012 Aug 15;206(4):523-33. doi: 10.1093/infdis/jis404. PubMed PMID: 22693228.