Research Area
Infectious Disease Research Services
Your Trusted Partner for Preclinical Infectious Disease Research
BIOQUAL provides preclinical infectious disease research services spanning viral, bacterial and parasitic pathogens. Our scientists combine in vivo models, in vitro assays, BSL-3 capabilities and custom model development to support vaccine, therapeutic and translational research programmes.
With decades of experience under our belt, our team is equipped to deliver a comprehensive suite of services, from therapeutic testing and vaccine research to developing custom assays for unique pathogen challenges. We combine scientific expertise with cutting-edge technology to support our clients’ diverse research needs, helping shape the future of therapeutics.
Integrated Infectious Disease Research Capabilities
BIOQUAL offers a full range of capabilities tailored to address the complex nature of viral, bacterial, and parasitic pathogens. Our services include:
Assay Development
With proven methodologies, we develop and optimize assays that ensure accurate, consistent results for a wide variety of targets.
Pathogen-Specific Studies
Our team has extensive experience in working with high-priority pathogens such as HIV, influenza, SARS-CoV-2, malaria and many more, providing reliable insights for R&D and preclinical testing. Our service offerings are also continuously evolving to meet global health needs and emerging threats.
Study Types: Pathogenesis, Vaccine Testing, Therapeutics Testing, Dose-ranging Studies, Infusion Dosing, BSL-3 (Including Select Agent) and BSL-2-requiring Studies, PK/Safety Testing
Infectious Disease Animal Models
BIOQUAL offers an array of preclinical animal models, including specialized non-human primate models, to enable in-depth study of infection mechanisms and therapeutic efficacy testing.
Don’t see the assay or model you need from the lists below?
Contact us to discuss your unique requirements—our team is committed to developing tailored solutions to meet your specific research goals.
Respiratory Viruses
(SARS-CoV-2, SARS-CoV-1, RSV, Influenza)
Viral
Mosquito-borne Viruses (Zika, Chikungunya, Dengue, Mayaro)
Viral
Human Immunodeficiency Virus (HIV/SHIV/SIV)
Viral
Orthopox Virus
Viral
Herpes Simplex Virus (HSV)
Viral
Viral Disease Research Services
Respiratory Viruses
(Influenza, RSV, SARS-CoV-1, SARS-CoV-2)
Animal Models
In vitro Services
Sample processing
qRT-PCR, TCID50, and plaque assay viral load testing
Binding antibody ELISA, HAI, ELLA, MN, and neutralization assays
Flow-based characterization and functional assays of immune cell populations
Cytokine/chemokine detection and analysis using ELISpot, Luminex, and ELISA
Virus stock generation in cells and embryonated chicken eggs
Testing available for various influenza A and B virus strains available (including seasonal and avian strains)
Antiviral assays
Custom assay development
Mosquito-borne Viruses (Zika, Chikungunya, Dengue, Mayaro)
Animal Models
IFNAR-/- mice (AG129), BALB/c, C57BL/6 mice
Non-human primates (NHP) including African green monkeys, rhesus and cynomolgus macaques
In vitro Services
Sample processing
qRT-PCR and plaque assay for viral load testing
Binding antibody ELISA and neutralization assays such as PRNT
Flow-based characterization and functional assays
Cytokine analysis using ELISpot and Luminex
Human Immunodeficiency Virus (HIV/SHIV/SIV)
Animal Models
Non-human primates
HIV/humanized mouse models
In vitro Services
Virus stock generation
Sample processing
Flow-based characterization and functional assays
Cytokine analysis using ELISpot and Luminex
qRT -PCR and TCID50 viral load testing
P24 and binding antibody ELISA
Orthopox Virus
Animal Models
Mpox : CAST/EiJ mice, rhesus and cynomolgus macaques
Vaccinia, cowpox, mouse pox: BALB/c mice
In vitro Services
Viral stock generation
Sample processing
qRT -PCR, TCID50and plaque assay for viral load testing
Binding antibody ELISA and PRNT
Flow-based characterization and functional assays
Cytokine analysis using ELISpot and Luminex
Herpes Simplex Virus (HSV)
Animal Models
Guinea Pig
Mouse
Rabbit
In vitro Services
Viral stock generation
Sample processing
qRT -PCR and plaque assay for viral load testing
Preclinical Bacterial Research Services
Staphylococcus aureus
Animal Models
NHPs
Mice
In vitro Services
Stock generation
Sample processing
Bacterial enumeration
Serological Testing
Flow cytometry and Luminex
Clostridium difficile
Animal Models
Mice
In vitro Services
Stock generation
Sample processing
Bacterial enumeration
Serological Testing
Flow cytometry and Luminex
Mycobacterium tuberculosis (Coming Soon)
Animal Models
Coming Soon
In vitro Services
Coming Soon
Preclinical Parasite Research Services
Malaria
Animal Models
BALB/c and CD1 mice
Rhesus macaque and squirrel monkeys
In vitro Services
Sample processing
Giemsa stained blood smears
Serological Testing
Advanced Laboratory Capabilities
BIOQUAL’s laboratories are designed to meet the highest safety and quality standards:
Biosafety Levels and Facilities
Our labs operate up to BSL-3 with select agent standards, ensuring the safe handling of highly infectious agents.
State-of-the-Art Technology
From immunoassays to advanced imaging, BIOQUAL’s technology stack supports complex research needs with precision.
Quality and Compliance
We are AAALAC-accredited and can run regulatory-compliant experiments for high-stakes preclinical studies and IND submissions.
